Apoptosis goes on in each living thing. It shapes the beginning life form of every animal and is behind the huge adjustments of caterpillars into butterflies and tadpoles into frogs. Some plant cells moreover deliberately execute themselves, for example, to stop an assaulting parasitic or bacterial tainting spreading. In run of the mill tissues there […]
Function and Structure of PKB PKB contains three isoforms with catalytic domains similar to those in the AGC kinase family. PKB? was initially discovered through homology cloning and the similar appearance of its kinase domain resembled that of protein kinase A and C therefore it was named protein kinase B (PKB). It has two family […]
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Order nowApoptosis is an event in which a cell is programmed and specifically sentenced to death. It happens naturally in the body. Apoptosis in greek means to fall off, and that’s one way to think about it. It’s as if one, or a few chosen cells are falling off a cliff, while the rest keep working. […]
Apoptosis is an important cellular process that allows cells to die in a programmed and organized fashion. This form of programmed cell death is crucial to the stability and equilibrium of living organisms. Such a process is shared amongst vertebrates and invertebrates alike (Miguel-Aliaga et al., 2009). It is easiest to define “normal” development by […]
All living cells will eventually decay and die. There are two recognized types of cell death: apoptosis and necrosis. Apoptosis refers to the “self-destruction” of a cell by its own mechanisms. Typically, a cell will undergo apoptosis when it is no longer able to repair itself. This could result from a number of possible cell […]
The basic concepts regarding the interactions between magnetic nanoparticles and a static or time-varying external magnetic field were reviewed. How these pertain to current biomedical applications of magnetic nanoparticles were also analyzed. The focus was in particular on magnetic separation and drug delivery. Although these are only two of the many biomedical applications of magnetic […]
Apoptosis is a form of preprogrammed cell death. It can occur if DNA is too damaged or if a cell is infected and cannot complete its function anymore. There are two pathways to trigger cell death. The extrinsic pathway begins the process through external ligand binding. The intrinsic pathway begins by releasing mitochondrial proteins into […]
Bioactive compounds, including polyphenols and phenolic acids or flavonoids, etc., have antioxidant and pro-oxidant properties. These compounds show high specificity because probably they act as an anti-oxidant and pro-oxidant. Approximately 60% of drugs currently used for cancer treatment have been isolated from natural products and the plant kingdom has been the most significant source. These […]
As a treatment of different cancer diseases, chemotherapy and radiotherapy are used on patients. Unfortunately radiotherapy may cause dangerous effects. Investigating these effects and determinations of risk reliable research. It is shown that IR’s most dangerous effect in cells are DBSs and that monitoring ?-H2AX focus numbers were useful biomarker to detect the invidual ionizing […]
This paper by Shen and collegues describes the role of the HIF-1 gene and the gene’s response to low oxygen levels in Caenorhabditis elegans (C. elegans). The hypoxia-inducible transcription factor (HIF-1) plays a critical role in being regulating systematic activities. The HIF-1? subunit contains proline residues which, in the presence of high oxygen levels are […]
Cells are constantly fighting between life and death. It is believed that once cells go through certain incidences, their death is irreversible. Incidences such as, shrinkage, the breakdown of DNA or mitochondria, condensation of the nucleus, as well as activation of caspases. A new ability to replenished cells was recently discovered; it is called anastasis. […]
Cell death is vital in the process of development, homeostasis and pathogenesis of acute and chronic Diseases resulting in tissue damage. apoptosis which is known to be Caspase dependent programmed cell death implicated in normal and disease pathogenesis. Ferroptosis is known to be distinct from other cell death modalities, based on their morphological, biochemical & […]
At a cellular basis, cancer cells are not that different from normal cells. In fact, from a biological view point cancer cells originate from normal cells. The features of a cancer cell; such as migrating away from its origin point, mutating and replicating itself, evading cell death and providing itself with a supply of oxygen […]
Introduction Hearing loss is the third most common disorder in the United States, being more prevalent than diabetes or cancer (Blackwell et al. 2014). Our ability to hear is dependent on hair cells that can translate the sounds we hear into electrical impulses that can be interpreted by the brain. When sounds waves enter the […]
Cells are the basic building blocks of life and make up all living organisms. There are two classifications of cells in every organism called prokaryotes and eukaryotes. A prokaryotic cell composes of single cell organisms like bacteria for example. While, a eukaryotic cell consists of multicellular organisms, the example for that is humans. The human […]
