Apoptosis Free Essay Examples And Topic Ideas

Cellular Death Process Study

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Cellular death is an essential biological process that occurs in all living organisms. It plays a critical role in development, maintenance, and defense mechanisms within the body. Two primary types of cellular death are necrosis and apoptosis, each with distinct characteristics and implications. Understanding these processes is vital for medical professionals and researchers as they navigate the complexities of human health and disease. This essay delves into the intricate mechanisms of necrosis and apoptosis, comparing their causes, processes, and outcomes, […]

Medicine

PKB and the Mitochondria: AKTing on Apoptosis

Words: 574 Pages: 2 4681

Function and Structure of PKB PKB contains three isoforms with catalytic domains similar to those in the AGC kinase family. PKB, initially discovered through homology cloning, maintained a similar appearance to protein kinase A and C in its kinase domain, and therefore, was named as Protein Kinase B (PKB). It has two family members: PKB/c-Akt2 (c-Akt is a cellular homologue of PKB) which is expressed mainly in insulin-target tissues, and PKB/c-Akt3 which is highly expressed in the brain and testis […]

Biotechnology

The Building Blocks of Life: Understanding Cells and their Impact

Words: 1006 Pages: 3 6312

Cells are the fundamental units of life, forming the intricate makeup of all living organisms. In every organism, cells fall into two primary classifications: prokaryotes and eukaryotes. Prokaryotic cells, which are typically single-celled organisms, include bacteria as a prime example. In contrast, eukaryotic cells make up multicellular organisms, with humans being a notable example. The human body is composed of an astounding 75 trillion cells, each serving a distinct purpose and function, contributing to the remarkable complexity of human anatomy. […]

Biotechnology Cancer Henrietta Lacks

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Cell Death Mechanism Analysis

Words: 688 Pages: 2 4836

Cell death is a fundamental biological process that plays a crucial role in maintaining the health and homeostasis of an organism. Among the various forms of cell death, apoptosis and necrosis are two distinct processes that serve different purposes. While apoptosis is a programmed and orderly process, necrosis is often chaotic and detrimental. This essay will explore the differences between apoptosis and necrosis, emphasizing their mechanisms, implications, and significance in both health and disease. Apoptosis: The Clean Executioner Apoptosis, often […]

Biotechnology Death Medicine

Apoptosis in each Living Thing

Words: 350 Pages: 1 4669

Apoptosis goes on in each living thing. It shapes the beginning life form of every animal and is behind the huge adjustments of caterpillars into butterflies and tadpoles into frogs. Some plant cells moreover deliberately execute themselves, for example, to stop an assaulting parasitic or bacterial tainting spreading. In run of the mill tissues there is a concordance between the period of new cells by methods for cell division and the loss of cells by methods for cell downfall. Old […]

Biotechnology

Cardiovascular System Disorders: Heart Disease

Words: 669 Pages: 2 4820

This 63-year-old man's history revealed that his father that died from a myocardial infarction (MI) which is the result of immediate occlusion of the blood flow to the coronary vessels. The most common causes of death from an MI are decreased cardiac output, fibrillation of the heart, rupture of the heart and pooling of the blood from pulmonary edema which resulted from the increased pressure within the heart. Symptoms presented by the patient are an indication to the healthcare staff […]

Cardiovascular Disease Disease Medicine

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The Vital Role of Apoptosis in Developmental Biology

Words: 1030 Pages: 3 4943

Apoptosis, a fundamental cellular process, enables cells to undergo programmed and organized death. Introduction This form of programmed cell death, or PCD, is indispensable for maintaining the stability and equilibrium of living organisms. It is a universal process observed across both vertebrates and invertebrates (Miguel-Aliaga et al., 2009). Understanding "normal" development often involves comparing it against what is considered abnormal, given that PCD has a distinguishable relationship with cell division and differentiation. When these processes fall out of balance, developmental […]

Death Neuroscience

Journal Article for Review: Apoptosis-induced CXCL5

Words: 1438 Pages: 5 4766

The article under review examines the acceleration of inflammation and growth of prostate tumor metastasis in bone due to apoptosis-induced CXCL5. Tumor cell death, which can be increased by targeted therapies, causes immense efferocytosis to clear the apoptotic cells. It is thought that this can lead to accelerated tumor growth. The scope of this research article is limited to prostate cancer cells and the proinflammatory cytokine, CKCL5, along with other variants. This article will exclude other ways of metastasis of […]

Biotechnology Cancer Immune System Journal Medicine Prostate Cancer

Stem Cells: Medical Frontiers

Words: 1068 Pages: 4 4851

Introduction A stem cell starts as an undifferentiated cell capable of self-renewal, producing daughter cells that remain as stem cells, or maturing into a specific cell type through differentiation (Can/Hematol 2008). The potency of a stem cell, or its ability to self-renew and differentiate, varies across types. For instance, one type of stem cell may differentiate into all adult cell types, while another can only mature into a single somatic cell type. The presence of stem cells is vital for […]

Biotechnology

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Intracellular Role of Apoptosis in In-Vivo Reactions Occurring in Multi-Cellular Organisms

Words: 1944 Pages: 6 4466

There are two well-known methods of cell execution: Apoptosis and Necrosis. Necrosis is regarded as a violent form of cell death, whereas apoptosis, on the other hand, is a more benign, modulated, and rational mode of killing cells. This process involves making well-informed decisions about selected cells to be terminated for the greater good of the host organisms. The advantages associated with the use of apoptosis as a regulated manner of programmed cell execution are well documented in literature. These […]

Biotechnology Chemistry

Cellular Death Mechanisms and Biological Implications

Words: 668 Pages: 2 4822

In the intricate dance of life, cellular processes operate in a delicate balance to maintain the body's overall health and functionality. Among these processes, cell death plays a critical role in the organism's lifecycle. Two primary forms of cell death, necrosis and apoptosis, demonstrate contrasting pathways and impacts on surrounding tissues. This essay explores these mechanisms, elucidating their causes, characteristics, and significance in physiological and pathological contexts. By understanding these processes, we gain insight into how the body maintains homeostasis […]

Death Literature Medicine

Advancements and Challenges in Cancer Treatment

Words: 947 Pages: 3 4948

Over the past five decades, significant advancements in cancer treatments have markedly increased the success rate of treating cancer patients. Abstract Prior to the 1990s, available options were largely limited to surgery or chemotherapy. However, recent scientific discoveries have unveiled crucial aspects of cancer biology, leading to the development of novel anti-cancer drugs that are less detrimental to the body. These innovative drugs, when used in conjunction with chemotherapy, constitute the predominant treatment strategy for most cancer patients today. Given […]

Cancer Literature Medicine

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How Cells Cheat Death

Words: 633 Pages: 2 5296

Cells are constantly fighting between life and death. It is believed that once cells go through certain incidences, their death is irreversible. Incidences such as, shrinkage, the breakdown of DNA or mitochondria, condensation of the nucleus, as well as activation of caspases. A new ability to replenished cells was recently discovered; it is called anastasis. Anastasis is a natural cell recovery that rescues cells from the brink of death (Tang, 2018). Its purpose is to save cells that are challenging […]

Biotechnology Cancer Death Medicine

Potential Mechanisms for Cancer Resistance in Elephants and Comparativage in Humans

Words: 687 Pages: 2 4914

It is expected that cancer risk would increase with body size and life span. Peto’s paradox describes the lack of correlation between body size, life span, and cancer risk (Caulin, 2011). The cellular mechanism behind this has only been experimentally demonstrated in rodents. TP53 is a gene that codes for the p53 protein. This gene is vital in tumor suppression, and is mutated in many human cancers (Jiang, 2018). Humans have one copy (2 alleles) of this gene. Both alleles […]

Biotechnology Cancer Genetics Literature Medicine

Frontiers in Pharmacology

Words: 1301 Pages: 4 4308

Summary of Research Method Applied In Vitro Studies: These studies give us useful information about the effects of Bryostatin-1 on the mechanisms involved in MS, such as oxidative stress. Explanation: Oxidative stress is an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants. Viability Tests: Explanation: This is an assay to determine the ability of organs, cells, or tissues to maintain or recover viability. For […]

Biotechnology Literature Multiple sclerosis Neuroscience Pharmacology

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Third most Likely Diagnosis

Words: 771 Pages: 3 4582

Systemic Lupus Erythematous (SLE) Systemic Lupus Erythematous (SLE) is a complex chronic autoimmune inflammatory disease of unknown cause, characterized by a variety of autoantibodies that attack self-components. It is mostly characterized by autoantibodies that attack nuclear antigens (McCance & Huether, 2014). Explain why the pathology is a possibility for this patient. Why do the clinical manifestations this patient has make you consider the pathophysiological problem? SLE is a chronic inflammatory disease that can attack any organ system, but it often […]

Immune System Literature Medicine

The Tumor Suppressor Role of TAp73 in Two Types of Cancer

Words: 1728 Pages: 6 4677

Transcription factor of p53 initiates apoptosis after receiving information about metabolic disorder or genetic damage, thus playing a critical role as tumor suppressor. p73 is a cousin of p53, shares lots of similarities with p53 including gene structure and amino acid level. Therefore, p73 is able to activate some p53 target genes by binding to p53-responsive elements when p53 is impaired. Also, p73 is rarely mutant compared to p53 in tumor cells. Whether p73 plays a role in tumor suppressor […]

Biotechnology Cancer Genetics Literature

The Role of Senescent Cells in Ageing and Cancer Suppression

Words: 1175 Pages: 4 5425

Senescent cells, often termed as "zombie cells," are somatic cells that, although no longer capable of dividing, display resistance to apoptosis, the process of programmed cell death (Scudellari, 2017). These cells accumulate in various body parts, exhibiting unique resistance to apoptosis, expressing distinct extracellular proteins, and secreting diverse molecules, including cytokines (Scudellari, 2017). This secretory activity is known as the cell's senescence-associated secretory phenotype (SASP). The presence of zombie cells and their SASPs can lead to various outcomes (Coppé, Desprez, […]

Biotechnology Genetics

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Cancer is a Vast Disease Category

Words: 2004 Pages: 7 5625

Abstract Cancer is a vast disease category that requires constant research for a cure. Over the decades, different treatment plans have arisen to try and combat the range of cancer cells. Some treatment has resulted in success, some end in death, and others are still an ongoing battle for the patients. Anti-cancer drugs have many side effects that come with them such as fatigue, inflammation, infection, and necrosis of cancerous cells. Cancer medicine has come a long way and now […]

Biotechnology Cancer Disease Medicine

Spinal Cord Injuries: Impacts and Advances in Treatment

Words: 834 Pages: 3 4575

Spinal cord injuries (SCIs) represent a significant medical challenge due to their complex nature and the profound impact they have on an individual's quality of life. Such injuries can lead to a multitude of consequences affecting the cellular structure and overall functioning of the spinal cord. This essay aims to delve into the intricate repercussions of SCIs at the cellular level, explore the physiological impacts, and discuss potential treatment strategies that could mitigate these effects. Through a detailed examination, we […]

Literature Neuroscience

Facts about Cells

Words: 333 Pages: 1 5031

All living cells will eventually decay and die. There are two recognized types of cell death: apoptosis and necrosis. Apoptosis refers to the “self-destruction” of a cell by its own mechanisms. Typically, a cell will undergo apoptosis when it is no longer able to repair itself. This could result from a number of possible cell injuries including viral infection, mutation, protein dysfunction, and DNA damage by way of free radicals. Apoptosis is implemented by enzymes called caspases, which have the […]

Medicine

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Annona Muricate and Annonaceous Acetogenins

Words: 1618 Pages: 5 5094

Introduction For the past decades cancer death has increase and remained one of the most high risk health concern in the world. According to the American Cancer Society, in 2019, there will be an estimated of 1,762,450 new cancer cases diagnose and 606,880 cancer death in the United States. Cancer occurs because of several changes in cell physiology that eventually replicate and produce harm to the body. There are more than 100 types of cancer, found in the human body […]

Biotechnology Cancer Literature Medicine

Potential Cancer Resistance

Words: 296 Pages: 1 4769

Cancer proliferation is characterized by uncontrolled and unregulated cell growth resulting in tumors. In theory, as the size of organism increases there are more cells developing and dividing meaning that this is an increased probability of cancer development. Although, this response is theorized this is not what actually occurs, but why this trend is observed remains poorly understood. The present study aimed to understand these mechanisms of cancer suppression in large, vertebrate mammals in hopes of gaining insight to human […]

Biotechnology Cancer Genetics

Cyclic GMP-AMP Synthase

Words: 385 Pages: 1 4444

Genomic DNA can be damaged by endogenous or environmental stresses. During repair, these short single-stranded DNAs are continuously generated and may leak out to the cytoplasm, where they are generally drawn back into the nucleus by DNA repair and replication factors (RPA and Rad51). Alongside this, TREX1, a cytoplasmic exonuclease, is anchored on the outer nuclear membrane to degrade leaking DNAs immediately. This prevents activation of the cGAS/STING pathway against self DNA. Inhibition of any of the above-mentioned proteins leads […]

Biotechnology Genetics Immune System

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Diffuse Intrinsic Pontine Gliomas

Words: 3372 Pages: 11 4607

Introduction/Epidemiology A diffuse intrinsic pontine glioma (DIPG), is a malignant tumor of the pons of the brainstem that originates in the supportive tissue called the glia. Specifically, these tumors are diffuse astrocytomas meaning that the tumor develops from astroglial cells of the brain stem. This tumor accounts for about 10%-20% of all brain tumors in children and roughly 80% of the 300-400 pediatric brainstem tumors that are diagnosed each year. The majority of children who develop this tumor type are […]

Biotechnology Cancer Genetics Immune System

Diosgenin in Colon Cancer

Words: 878 Pages: 3 4737

The author noted that diosgenin constrains the 3-hydroxy-3-methylglutaryl CoA reductase expression and stimulates apoptosis in human colon tumor cells. Diosgenin is also a potent inhibitor of HCT-116 with growth inhibition and induction of apoptosis [39]. Diosgenin induces apoptosis via the cyclooxygenase-2 and 5-lipoxygenase pathways in HT-29 and HCT-116 [40]. The author described diosgenin's ability to enhance 5-LOX activity; its inhibition by AA-861 notably reduces the apoptosis of colorectal tumor cells. Moreover, colorectal carcinoma cells expressing COX-2 are less sensitive to […]

Biotechnology Cancer

Traditional Chinese Medicine Essay

Words: 1515 Pages: 5 6998

Introduction Traditional Chinese Medicine (TCM) is a type of holistic, natural health care system with its origin deeply rooted in the ancient philosophy of Taoism. The practice of TCM dates back more than 2500 years and it is regarded as one of the oldest forms of medicines. Chinese herbal medicines are a very important component of TCM, which also includes other mind and body practices like acupuncture, moxibustion (burning an herb above the skin to apply heat to acupuncture points), […]

Cancer Medicine

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The Immune System – Immunity

Words: 1563 Pages: 5 5181

The immune system is a structure of bodily safeguards that protect the human body from antigens such as infectious and venomous agents. This system recognizes, processes, and then eliminates antigens. Based on descriptions and memory, the immune system deterrence is categorized into two types: innate and adaptive immunity. The coordination and development of a well-adjusted mechanism to obliterate pathogens are shared by both systems. Specific elements acclimate themselves to each new class of illness encountered and are hence able to […]

Immune System Medicine

Diseases are Associated with Cell Death

Words: 377 Pages: 1 4884

Regulation of cell death is vital for development, pathogenesis, and homeostasis. Both acute and chronic diseases are associated with excessive cell death, which results in tissue damage. Caspase-dependent apoptosis is a type of programmed cell death implicated in both normal and disease pathogenesis. Ferroptosis is distinct from other cell death modalities based on morphological, biochemical, and genetic criteria. Ferroptosis is a pathogenic programmed cell death characterized by the iron-mediated production of toxic lipid hydroperoxides. This unique form of cell death […]

Biotechnology Chemistry Death Medicine

Accelerated Inflammation and Cancer Metastases

Words: 1226 Pages: 4 5029

Background Prostate cancer is one of the most common forms of cancer that can metastasize to the bone. The mechanism of how cancer cells break away from their primary origin and travel through the bloodstream to the bone is a process that is still unclear to many scientists (“Bone Metastasis,” 2018). Once cancer cells reach the bone, they become a part of an environment where it is easy for the cells to become mobile, proliferate, and differentiate to proinflammatory cells. […]

Biotechnology Cancer Experiment Medicine Prostate Cancer

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